Symptoms

Some symptoms are:

• Cry that is high-pitched and sounds like a cat
• Downward slant to the eyes
• Low birth weight and slow growth
• Low-set or abnormally shaped ears
• Partial webbing of fusing of fingers and toes
• Single line on the palm of the hand (simian crease)
• Skin tags just in front of the ear
• Slow or incomplete development of motor skills
• Small head
• Small jaw
• Wide-set eyes